Type 1 And Type 2 Diabetes 3d Model. But it can still cause major health complications especially in the tiny blood vessels in your kidneys nerves and eyes. The type 1 diabetes simulation model is built around a series of key health states and interlinking dependencies.
We generated high resolution maps of linear and 3d genome organization in thymocytes of nod mice a model of type 1 diabetes t1d and the diabetes resistant c57bl 6 mice. But it can still cause major health complications especially in the tiny blood vessels in your kidneys nerves and eyes. In humans both type 1 and type 2 diabetes exemplify genetically heterogeneous complex diseases in which epigenetic factors contribute to underlying genetic susceptibility.
The animal model chosen will depend on whether a model of type 1 or type 2 diabetes is required.
Extended human pedigrees often show inheritance of both diabetes types. Introduction type 1 diabetes. According to the diabetes atlas international diabetes federation 2013 8 10 of the world population between 20 and 80 years suffers from diabetes this amounts to 380 million people in 2013 growing to 590 million in 2035. Alternatively pancreatectomized miniature swine have been recognized as an excellent model for studying the vascular changes associated with type 1 dm.
